CellaVision® Bone Marrow Aspirate Application
Description
Digital Bone Marrow Aspirate Morphology Review Software
The CellaVision® Bone Marrow Aspirate (BMA) Application automatically locates, captures, and pre-classifies cells based on morphology, enabling laboratories to automate, standardize, and simplify morphological examination of bone marrow aspirate samples.
Designed for use on the CellaVision® DC-1 analyzer, the application supports efficient, traceable, and collaborative review of bone marrow aspirate differentials.
What the Bone Marrow Aspirate Application Supports
The application enables:
- Nucleated cell differential, delivering comprehensive pre-classification into 17 cell types
- Automatic location of suitable areas for the differential
- Manual selection of differential areas when desired
- Remote review by several experts, including preliminary signatures and extensive commenting functions
- Reporting of results to LIS or generation of a PDF report including selected cell images
- Traceability in area selection, re-classification, commenting, and results
This functionality helps laboratories automate and standardize bone marrow aspirate morphological examination while maintaining expert verification and documentation.
A Complete Workflow for Bone Marrow Aspirate Review
The CellaVision BMA Application runs on a CellaVision® DC-1 analyzer using a 100x objective. Together with CellaVision® BMA Review Software, it enables morphology review, consultation, and verification of bone marrow aspirate cell differentials from anywhere, at any time.
The workflow includes:
- Automatic location, capture, and storage of bone marrow aspirate cells based on morphology
- AI-powered pre-classification
- Digital display of stored cell images for expert review and verification
How It Works
Automated Location and Pre-Classification
CellaVision® BMA Analyzer Software automatically locates, pre-classifies, and stores bone marrow aspirate cells based on morphology, using advanced AI technology.
Expert Review and Verification
With CellaVision® BMA Review Software, the cell images are displayed, and the pre-classification results are reviewed and verified by a qualified bone marrow morphology expert.
This workflow supports standardized morphology assessment while maintaining professional oversight.
Why CellaVision® Bone Marrow Aspirate Application?
The CellaVision BMA Application transforms bone marrow analysis by turning aspirates into answers:
- Automates manual work with AI-powered cell pre-classification in a user-friendly, collaborative workflow
- Promotes accuracy and consistency through standardization, traceable images, and reference tools
- Enables remote review to support collaboration, turnaround time, diagnostic confidence, and proficiency
Technical specifications
Wedge smear or Squash preparation, with or without coverslip
• Manual smears
• Automated or manual staining
• RAL StainBox and RAL Stainer
Romanowsky stains
• May Grünwald Giemsa
• Wright Giemsa
• Wright
• RAL MCDh
• Differential pre-classification: Proerythroblast, Basophilic erythroblast*, Polychromatic erythroblast, Orthochromatic erythroblast, Blast, Promyelocyte, Myelocyte, Metamyelocyte, Band neutrophil, Segmented neutrophil, Eosinophil, Basophil*, Monocyte, Mast cell*, Lymphocyte, Plasma cell
• Other cells and artifacts pre-classified: Macrophage, Smudge cell, Artifact
• User has the ability to add additional cell classes for manual re-classification
• Dysplastic cells: quantitative results presented as the percentage of cells in lineage tagged by the user as dysplastic in the erythroid and myeloid lineages
• M:E ratio: quantitative results presented as the M:E ratio based on user classified cells in the Myeloid and Erythroid lineage
• Results can be saved in a PDF-report as well as sent to LIS
• CellaVision® DC-1 – A small footprint analyzer providing high quality images acquired with a 100X oil objective which can be operated as a stand-alone device or in a network configuration
• CellaVision® DC-1 analyzer is supplied with CellaVision® Peripheral Blood Application as a standard feature
* The application generally reports lower values for Basophilic erythroblasts, Basophils and Mast cells compared to manual microscopy, based on performance evaluation studies.
** The clinical performance evaluation included samples from patients across various age groups, including pediatric cases. However, the number of pediatric samples was not sufficient to draw statistically robust conclusions specific to this subpopulation. Therefore, the clinical performance in pediatric patients has not been fully demonstrated.
Specifications are subject to change without notice. This product may not be available in all markets.
Digital Bone Marrow Aspirate Morphology Review Software
The CellaVision® Bone Marrow Aspirate (BMA) Application automatically locates, captures, and pre-classifies cells based on morphology, enabling laboratories to automate, standardize, and simplify morphological examination of bone marrow aspirate samples.
Designed for use on the CellaVision® DC-1 analyzer, the application supports efficient, traceable, and collaborative review of bone marrow aspirate differentials.
What the Bone Marrow Aspirate Application Supports
The application enables:
- Nucleated cell differential, delivering comprehensive pre-classification into 17 cell types
- Automatic location of suitable areas for the differential
- Manual selection of differential areas when desired
- Remote review by several experts, including preliminary signatures and extensive commenting functions
- Reporting of results to LIS or generation of a PDF report including selected cell images
- Traceability in area selection, re-classification, commenting, and results
This functionality helps laboratories automate and standardize bone marrow aspirate morphological examination while maintaining expert verification and documentation.
A Complete Workflow for Bone Marrow Aspirate Review
The CellaVision BMA Application runs on a CellaVision® DC-1 analyzer using a 100x objective. Together with CellaVision® BMA Review Software, it enables morphology review, consultation, and verification of bone marrow aspirate cell differentials from anywhere, at any time.
The workflow includes:
- Automatic location, capture, and storage of bone marrow aspirate cells based on morphology
- AI-powered pre-classification
- Digital display of stored cell images for expert review and verification
How It Works
Automated Location and Pre-Classification
CellaVision® BMA Analyzer Software automatically locates, pre-classifies, and stores bone marrow aspirate cells based on morphology, using advanced AI technology.
Expert Review and Verification
With CellaVision® BMA Review Software, the cell images are displayed, and the pre-classification results are reviewed and verified by a qualified bone marrow morphology expert.
This workflow supports standardized morphology assessment while maintaining professional oversight.
Why CellaVision® Bone Marrow Aspirate Application?
The CellaVision BMA Application transforms bone marrow analysis by turning aspirates into answers:
- Automates manual work with AI-powered cell pre-classification in a user-friendly, collaborative workflow
- Promotes accuracy and consistency through standardization, traceable images, and reference tools
- Enables remote review to support collaboration, turnaround time, diagnostic confidence, and proficiency
Wedge smear or Squash preparation, with or without coverslip
• Manual smears
• Automated or manual staining
• RAL StainBox and RAL Stainer
Romanowsky stains
• May Grünwald Giemsa
• Wright Giemsa
• Wright
• RAL MCDh
• Differential pre-classification: Proerythroblast, Basophilic erythroblast*, Polychromatic erythroblast, Orthochromatic erythroblast, Blast, Promyelocyte, Myelocyte, Metamyelocyte, Band neutrophil, Segmented neutrophil, Eosinophil, Basophil*, Monocyte, Mast cell*, Lymphocyte, Plasma cell
• Other cells and artifacts pre-classified: Macrophage, Smudge cell, Artifact
• User has the ability to add additional cell classes for manual re-classification
• Dysplastic cells: quantitative results presented as the percentage of cells in lineage tagged by the user as dysplastic in the erythroid and myeloid lineages
• M:E ratio: quantitative results presented as the M:E ratio based on user classified cells in the Myeloid and Erythroid lineage
• Results can be saved in a PDF-report as well as sent to LIS
• CellaVision® DC-1 – A small footprint analyzer providing high quality images acquired with a 100X oil objective which can be operated as a stand-alone device or in a network configuration
• CellaVision® DC-1 analyzer is supplied with CellaVision® Peripheral Blood Application as a standard feature
* The application generally reports lower values for Basophilic erythroblasts, Basophils and Mast cells compared to manual microscopy, based on performance evaluation studies.
** The clinical performance evaluation included samples from patients across various age groups, including pediatric cases. However, the number of pediatric samples was not sufficient to draw statistically robust conclusions specific to this subpopulation. Therefore, the clinical performance in pediatric patients has not been fully demonstrated.
Specifications are subject to change without notice. This product may not be available in all markets.
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