Hematopoiesis is a process of blood cell production and maturation in the bone marrow.
The process begins with the pluripotent stem cell.
The stem cell is capable to proliferate, differentiate and replicate.
The differentiation into a myeloid or lymphoid stem cell takes place in response of growth factors (cytokines).
The lymphoid stem cell differentiates into a pre-B or pre-T stem cell. The myeloid stem cell produces an intermediate stem cell which differentiates into erythroid, megakarycytic, myeloid, monocytic, eosinophilic or basophilic lineage.
The most immature stem cells cannot be morphologically identified.